Monkeypox is a rare viral infection caused by an orthopoxvirus, which is a relatively large DNA virus that is related to smallpox. Monkeypox received its name because it was discovered in a group of laboratory monkeys in 1958. However, rodents, and not monkeys, are the most likely animal reservoir. Occasionally, monkeypox causes zoonotic infections in…

Monkeypox is a rare viral infection caused by an orthopoxvirus, which is a relatively large DNA virus that is related to smallpox. Monkeypox received its name because it was discovered in a group of laboratory monkeys in 1958. However, rodents, and not monkeys, are the most likely animal reservoir. Occasionally, monkeypox causes zoonotic infections in…

As of May 6, 2022, The Centers for Disease Control and Prevention (CDC) has received 109 reports of unexplained hepatitis in young children from 24 states and Puerto Rico. Ninety percent of the children have been hospitalized and 14% have required liver transplants. Five children have died. Most of the children have recovered, though some…

The patient is lying sick in bed The history we have not read Nor laid a hand upon his head Whatever shall we do?   Well, first we’ll order lots of tests. STAT orders 24 x 7 to give it our best Start with CBC, CRP, LFT and BMP An ANA and hepatitis viruses A,…

Hereditary transthyretin amyloidosis cardiomyopathy (hATTR-CM) is an autosomal-dominant cardiac disease caused by a mutation in the TTR gene that results in a substitution of isoleucine for valine at position 122 (TTR Val122Ile) in transthyretin, which is also called thyroxine and retinol transport protein. This substitution causes a conformational change in the tetrameric subunits of transthyretin that…